Chemoembolization
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GAME
CHANGE UN.
BE. LEAVE-ABLE. Wait until you read this
book. To think John Edwards got as far as he did. Appalling. And there’s plenty in the book about everybody else.
On so many pages, you are watching the events we all saw from our side
of the TV screen, only now you’re seeing them from the inside.
I
don’t think there’s much risk of your putting down Game Change
once you start reading. But don’t, because near the end you get to
the parts on Senator McCain and Governor Palin. I think even if you voted for them –
and it’s worth noting that nearly 60 million people did – you may
feel more than a little relieved they did not win. Take
the financial meltdown. Remember? When Senator McCain temporarily
suspended his campaign to come to Washington to assert his leadership?
This was not some silliness about Obama’s not wearing a lapel pin or McCain’s
shouting obscenities at his wife – this was a true crisis that came close
to wrecking our world. The
authors recount those events from the inside and then (page 393) offer the
perspective of one of the insiders: Jim Wilkinson, a long-time Republican operative,
served as [Treasury Secretary Henry] Paulson’s chief of staff during the
crisis, and his impression of the candidates could hardly have been
clearer. “I’m a pro-life, pro-gun, Texas Republican,”
said Wilkinson. “I worked all eight years for Bush. I helped
sell the Iraq war. I was in the Florida recount. And I wrote a
letter to John McCain asking for my five hundred dollar contribution back
. . .” To his amazement, Wilkinson determined that he would be
voting for Obama. FRANK
RICH: TIME TO GET TOUGH ALAN
GRAYSON: HAS A PETITION “The same five judges today who
have overturned 103 years of settled law and relied upon no precedent to do
so,” says the Florida Congressman – “these are the same
judges who gave us George Bush for eight years. They have their own
agenda and it`s time we stopped pretending otherwise. The Supreme Court
has become utterly politicized and the result of that is what you see here
today. … Today, the court, in effect, decided only corporations have
constitutional rights. This will lead to a drowning flood of money from
corporations in exchange for favors. And it basically
institutionalizes and legalizes bribery on the largest scale imaginable.
Corporations will now be able to reward the politicians that play ball with
them and will be able – they will be able to beat to death the
politicians that don`t.” Read more; sign his petition? Dcth So
Thursday, I suggested
this as a possible third egg for our speculative little drug stock
basket. It had closed the night before at $5.37. Friday, it dropped
to $4.61. “I
think DCTH was down
Friday,” guru offers, “because ONXX’s Nexavar showed no
statistical benefit in a 400-patient trial when given with or without
chemoembolization of the liver in liver cancer. Chemoembolization is a
kind of precursor to DCTH’s procedure – it adds high dose chemo
plus a chemical to block the artery so the chemo is forced through the
tumor. However, eventually the chemo ends up exiting the liver via a
vein. Thus, there is a limit to how much chemo you can give with this
procedure. The DCTH method can deliver 20 to 50 times higher doses of
chemo than can chemoembolization. It’s really amazing.
Chemoembolization shows some shrinkage of the tumor in 20%-40% of
patients with melanoma metastatic to the liver. DCTH shows 20%
complete disappearance and 60% partial shrinkage – a MUCH more dramatic
result. The data are due out in April and I feel as confident as one can
be at this stage that they will show the success that ONXX did not.” ☞
But one never knows, so – as usual – bet no more on this than you
can truly afford to lose without recrimination. I can live with their
canceling Dirty, Sexy
Money. I can live (barely) with paying $1.50 for a hotel newsstand
pack of Dentyne
Ice if I’ve forgotten to take one of my 90-cent packs from
home. But your recriminations? Tomorrow:
More reason to get tough.
© 1998, 1999, 2000, 2001, 2002, 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010 Andrew Tobias